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CBD interacts with common medications — the "grapefruit rule" applies

STRONG EVIDENCE CBD

CBD inhibits CYP450 enzymes (notably CYP3A4 and CYP2C19) that metabolize many drugs: blood thinners, anti-epileptics, some antidepressants. If a medication carries a grapefruit warning, treat CBD the same way and ask a pharmacist.

What "strong evidence" means here:
Convergent evidence: controlled trials, systematic reviews, or long-established pharmacology.

Sources & further reading

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