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Beta-caryophyllene is a dietary cannabinoid

STRONG EVIDENCE Terpenes & Entourage

The peppery terpene β-caryophyllene — also in black pepper and cloves — directly activates CB2 receptors. It is the best-documented case of a terpene acting like a cannabinoid, demonstrated by Gertsch et al. in 2008.

What "strong evidence" means here:
Convergent evidence: controlled trials, systematic reviews, or long-established pharmacology.

Sources & further reading

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